Title : Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications.

Pub. Date : 2018 Jun 19

PMID : 29678953






4 Functional Relationships(s)
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1 In some highland populations, there has also been a selection of variants in PPARA, encoding peroxisome proliferator-activated receptor alpha (PPARalpha), a transcriptional regulator of fatty acid metabolism. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
2 In some highland populations, there has also been a selection of variants in PPARA, encoding peroxisome proliferator-activated receptor alpha (PPARalpha), a transcriptional regulator of fatty acid metabolism. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
3 In some highland populations, there has also been a selection of variants in PPARA, encoding peroxisome proliferator-activated receptor alpha (PPARalpha), a transcriptional regulator of fatty acid metabolism. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
4 In one such population, the Sherpas, lower muscle PPARA expression is associated with a decreased capacity for fatty acid oxidation, potentially improving the efficiency of oxygen utilisation. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens