Title : Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury.

Pub. Date : 2018 May 1

PMID : 29670094






1 Functional Relationships(s)
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1 Mechanistically, DEPTOR modulated p38 MAPK signaling and TNFalpha production in vivo and in vitro, rather than mTOR signaling, thus moderating the inflammatory response and cell apoptosis induced by cisplatin. Cisplatin tumor necrosis factor Mus musculus