Pub. Date : 2018 Jul 1
PMID : 29665354
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PRMT1 negatively regulates activation-induced cell death in macrophages by arginine methylation of GAPDH. | Arginine | protein arginine methyltransferase 1 | Homo sapiens |
2 | Here, we found that protein arginine methyltransferase 1 (PRMT1) mediated arginine methylation of GAPDH in primary bone marrow-derived macrophages in a NO-dependent manner. | Arginine | protein arginine methyltransferase 1 | Homo sapiens |
3 | Taken together, our results suggest that PRMT1 has a previously unrecognized function to inhibit activation-induced cell death of macrophages through arginine methylation of GAPDH. | Arginine | protein arginine methyltransferase 1 | Homo sapiens |