Title : PRMT1 negatively regulates activation-induced cell death in macrophages by arginine methylation of GAPDH.

Pub. Date : 2018 Jul 1

PMID : 29665354






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PRMT1 negatively regulates activation-induced cell death in macrophages by arginine methylation of GAPDH. Arginine protein arginine methyltransferase 1 Homo sapiens
2 Here, we found that protein arginine methyltransferase 1 (PRMT1) mediated arginine methylation of GAPDH in primary bone marrow-derived macrophages in a NO-dependent manner. Arginine protein arginine methyltransferase 1 Homo sapiens
3 Taken together, our results suggest that PRMT1 has a previously unrecognized function to inhibit activation-induced cell death of macrophages through arginine methylation of GAPDH. Arginine protein arginine methyltransferase 1 Homo sapiens