Pub. Date : 2018 Jun 1
PMID : 29650681
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we found that YAP/TAZ directly regulate expression of key enzymes involved in deoxynucleotide biosynthesis and maintain dNTP precursor pools in human cancer cells. | deoxynucleotide | Yes1 associated transcriptional regulator | Homo sapiens |
| 2 | Regulation of deoxynucleotide metabolism is required for YAP-induced cell growth and underlies the resistance of YAP-addicted cells to chemotherapeutics targeting dNTP synthesis. | deoxynucleotide | Yes1 associated transcriptional regulator | Homo sapiens |
| 3 | Regulation of deoxynucleotide metabolism is required for YAP-induced cell growth and underlies the resistance of YAP-addicted cells to chemotherapeutics targeting dNTP synthesis. | deoxynucleotide | Yes1 associated transcriptional regulator | Homo sapiens |