Title : Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation.

Pub. Date : 2018 May 10

PMID : 29649741






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compounds ZL0420 (28) and ZL0454 (35) were identified as potent and selective BRD4 inhibitors with nanomolar binding affinities to bromodomains (BDs) of BRD4. CHEMBL4159382 bromodomain containing 4 Homo sapiens
2 Compounds ZL0420 (28) and ZL0454 (35) were identified as potent and selective BRD4 inhibitors with nanomolar binding affinities to bromodomains (BDs) of BRD4. CHEMBL4159382 bromodomain containing 4 Homo sapiens