Pub. Date : 2018 Apr 11
PMID : 29642873
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bexarotene inhibits the viability of non-small cell lung cancer cells via slc10a2/PPARgamma/PTEN/mTOR signaling pathway. | Bexarotene | solute carrier family 10 member 2 | Homo sapiens |
| 2 | In addition, overexpressed slc10a2 in NSCLC cells can further suppress the proliferation and migration, and promote apoptosis under the treatment of bexarotene. | Bexarotene | solute carrier family 10 member 2 | Homo sapiens |
| 3 | On the contrary, the opposite results were obtained after slc10a2 gene was silenced in NSCLC cells treated with bexarotene. | Bexarotene | solute carrier family 10 member 2 | Homo sapiens |
| 4 | CONCLUSION: These results suggest that bexarotene inhibits the viability of lung cancer cells via slc10a2/PPARgamma/PTEN/mTOR signaling pathway. | Bexarotene | solute carrier family 10 member 2 | Homo sapiens |