Title : Suppressive effects of metformin on T-helper 1-related chemokines expression in the human monocytic leukemia cell line THP-1.

Pub. Date : 2018 Nov

PMID : 29630425






4 Functional Relationships(s)
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1 Suppressive effects of metformin on T-helper 1-related chemokines expression in the human monocytic leukemia cell line THP-1. Metformin GLI family zinc finger 2 Homo sapiens
2 We investigated the anti-inflammatory mechanism of metformin in the human monocytic leukemia cell line THP-1. Metformin GLI family zinc finger 2 Homo sapiens
3 MATERIALS AND METHODS: The human monocytic leukemia cell line THP-1 was pretreated with metformin and stimulated with lipopolysaccharide (LPS). Metformin GLI family zinc finger 2 Homo sapiens
4 CONCLUSIONS: Metformin suppressed the production of Th1-related chemokines IP-10 and MCP-1 in THP-1 cells. Metformin GLI family zinc finger 2 Homo sapiens