Pub. Date : 2018 Jun 21
PMID : 29592891
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase. | Vitamin K | vitamin K epoxide reductase complex subunit 1 | Homo sapiens |
| 2 | The anticoagulant warfarin inhibits the vitamin K oxidoreductase (VKORC1), which generates vitamin K hydroquinone (KH2) required for the carboxylation and consequent activation of vitamin K-dependent (VKD) proteins. | Vitamin K | vitamin K epoxide reductase complex subunit 1 | Homo sapiens |