Title : Synergistic anti-proliferative effects of combination of ABT-263 and MCL-1 selective inhibitor A-1210477 on cervical cancer cell lines.

Pub. Date : 2018 Mar 27

PMID : 29580266






1 Functional Relationships(s)
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1 Hence, the aim of this pilot study is to investigate the sensitivity of cervical cancer cell lines to combination of two BH3-mimetics namely ABT-263 which selectively inhibits BCL-2, BCL-XL and BCL-w and A-1210477, a selective MCL-1 inhibitor. BH 3 MCL1 apoptosis regulator, BCL2 family member Homo sapiens