Pub. Date : 2018 May
PMID : 29565447
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CAFs enhance paclitaxel resistance by inducing EMT through the IL-6/JAK2/STAT3 pathway. | Paclitaxel | interleukin 6 | Homo sapiens |
| 2 | These results demonstrated that CAFs highly secreted IL-6 and promoted beta-TGF-mediated EMT in ovarian cancer via the JAK2/STAT3 pathway, leading to inhibited apoptosis and subsequent paclitaxel resistance. | Paclitaxel | interleukin 6 | Homo sapiens |