Title : Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated.

Pub. Date : 2018 Mar 15

PMID : 29543732






1 Functional Relationships(s)
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1 IS promoted phosphorylation of NF-kappaB p65 and MAPK enzymes; the reaction and IL-1 expression were inhibited by BAY11-7082, an inhibitor of NF-kappaB. 3-(4-methylphenylsulfonyl)-2-propenenitrile interleukin 1 alpha Homo sapiens