Title : Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions.

Pub. Date : 2018 Mar 13

PMID : 29535353






2 Functional Relationships(s)
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1 In light of recent experimental data, we have performed several long-timescale molecular dynamics (MD) simulations, totalling 24 mus, to rigorously map allosteric modulation and conformational changes in the beta2 adrenergic receptor (beta2AR) that occur as a result of interactions with three different phospholipids. Phospholipids adrenoceptor beta 2 Homo sapiens
2 In light of recent experimental data, we have performed several long-timescale molecular dynamics (MD) simulations, totalling 24 mus, to rigorously map allosteric modulation and conformational changes in the beta2 adrenergic receptor (beta2AR) that occur as a result of interactions with three different phospholipids. Phospholipids adrenoceptor beta 2 Homo sapiens