Title : In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile-Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa.

Pub. Date : 2018 Apr

PMID : 29529473






1 Functional Relationships(s)
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1 BAY 11-7082 eliminates NF-kappaB activation in regenerating basal cells of acidic bile-treated HM and prevents overexpression of molecules central to head and neck cancer, including bcl-2, STAT3, EGFR, TNF-alpha, and WNT5A. 3-(4-methylphenylsulfonyl)-2-propenenitrile tumor necrosis factor Mus musculus