Title : Comparative Proteomic Identification of Protein Disulphide Isomerase A6 Associated with Tert-Butylhydroperoxide-Induced Liver Injury in Rat Hepatocytes.

Pub. Date : 2018

PMID : 29518773






2 Functional Relationships(s)
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1 t-BHP-dependent induction of apoptosis was accompanied by sustained phosphorylation of the IRE1alpha/ASK1/JNK1/2/p38 pathways and PDIA6 expression. tert-Butylhydroperoxide endoplasmic reticulum (ER) to nucleus signalling 1 Mus musculus
2 Furthermore, t-BHP induced liver FL83B cell viability and apoptosis by upregulating the levels of PDIA6; this process could be involved in the activation of the IRE1alpha/ASK1/JNK1/2/p38 signalling pathways. tert-Butylhydroperoxide endoplasmic reticulum (ER) to nucleus signalling 1 Mus musculus