Title : miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension.

Pub. Date : 2018 Mar

PMID : 29511611






2 Functional Relationships(s)
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1 Here, we show that miR-322-5p (the rodent orthologue of miR-424-5p) expression is decreased in the right ventricle of monocrotaline-treated rats, a model of PAH, whereas a putative target insulin-like growth factor 1 (IGF-1) is increased. Monocrotaline insulin-like growth factor 1 Rattus norvegicus
2 Here, we show that miR-322-5p (the rodent orthologue of miR-424-5p) expression is decreased in the right ventricle of monocrotaline-treated rats, a model of PAH, whereas a putative target insulin-like growth factor 1 (IGF-1) is increased. Monocrotaline insulin-like growth factor 1 Rattus norvegicus