Title : MicroRNA-223 is involved in the pathogenesis of atopic dermatitis by affecting histamine-N-methyltransferase.

Pub. Date : 2018 Feb 28

PMID : 29506638






3 Functional Relationships(s)
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1 What"s more, we found for the first time that one of the major histamine degradation enzymes, histamine-N-methyltransferase (HNMT), was increased in AD patients and AD model mice. Histamine histamine N-methyltransferase Homo sapiens
2 What"s more, we found for the first time that one of the major histamine degradation enzymes, histamine-N-methyltransferase (HNMT), was increased in AD patients and AD model mice. Histamine histamine N-methyltransferase Homo sapiens
3 Taken together, it suggested that miR-223 participates in AD through upregulating HNMT indirectly to degrade the excessive histamine. Histamine histamine N-methyltransferase Homo sapiens