Pub. Date : 2018 Jun 3
PMID : 29504819
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of miR-144 on the sensitivity of human anaplastic thyroid carcinoma cells to cisplatin by autophagy regulation. | Cisplatin | microRNA 144 | Homo sapiens |
| 2 | BACKGROUND: We investigated the influence of miR-144 on the cisplatin-sensitivity of anaplastic thyroid carcinoma (ATC) cells and explored the internal molecular mechanism of miR-144. | Cisplatin | microRNA 144 | Homo sapiens |
| 3 | RESULTS: MiR-144, which was low expressed in ATC cells and tissues, could inhibit autophagy activation induced by cisplatin, enhancing the sensitivity of ATC cells to cisplatin, and promoting cell apoptosis. | Cisplatin | microRNA 144 | Homo sapiens |
| 4 | RESULTS: MiR-144, which was low expressed in ATC cells and tissues, could inhibit autophagy activation induced by cisplatin, enhancing the sensitivity of ATC cells to cisplatin, and promoting cell apoptosis. | Cisplatin | microRNA 144 | Homo sapiens |
| 5 | MiR-144 could improve the sensitivity of ATC cells to cisplatin and inhibit tumor growth by suppressing TGF-alpha both in vitro and in vivo. | Cisplatin | microRNA 144 | Homo sapiens |
| 6 | CONCLUSION: MiR-144 could inhibit autophagy of ATC cells by down-regulating TGF-alpha, enhancing the cisplatin-sensitivity of ATC cells. | Cisplatin | microRNA 144 | Homo sapiens |