Title : Bach2 regulates aberrant activation of B cell in systemic lupus erythematosus and can be negatively regulated by BCR-ABL/PI3K.

Pub. Date : 2018 Apr 1

PMID : 29501569






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Further, LY294002 treatment had no effect on decreased expression of Bach2 induced by BCR-ABL, but significantly eliminated BCR-ABL-induced phosphorylation of Bach2 and restored reduced nuclear translocation of Bach2 induced by BCR-ABL in B cells from SLE. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 Further, LY294002 treatment had no effect on decreased expression of Bach2 induced by BCR-ABL, but significantly eliminated BCR-ABL-induced phosphorylation of Bach2 and restored reduced nuclear translocation of Bach2 induced by BCR-ABL in B cells from SLE. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens