Title : Self-interaction of NPM1 modulates multiple mechanisms of liquid-liquid phase separation.

Pub. Date : 2018 Feb 26

PMID : 29483575






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pentameric NPM1 undergoes liquid-liquid phase separation (LLPS) via heterotypic interactions with nucleolar components, including ribosomal RNA (rRNA) and proteins which display multivalent arginine-rich linear motifs (R-motifs), and is integral to the liquid-like nucleolar matrix. Arginine nucleophosmin 1 Homo sapiens