Title : Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation.

Pub. Date : 2018 Dec

PMID : 29470999






2 Functional Relationships(s)
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1 METHODS: Isolated dendritic cells and bone marrow-derived mast cells (MCs) were used to characterize the mechanisms of action of NAD+ on CD4+ T-cell fate in vitro. NAD CD4 antigen Mus musculus
2 Furthermore, NAD+-mediated CD4+ T-cell differentiation was investigated in vivo by using wild-type C57BL/6, MC-/-, MHC class II-/-, Wiskott-Aldrich syndrome protein (WASP)-/-, 5C.C7 recombination-activating gene 2 (Rag2)-/-, and CD11b-DTR transgenic mice. NAD CD4 antigen Mus musculus