Title : Cross-species comparison of the metabolism and excretion of selexipag.

Pub. Date : 2019 Mar

PMID : 29468921






1 Functional Relationships(s)
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1 The metabolism of the prostacyclin receptor agonist selexipag (NS-304; ACT-293987) and its active metabolite MRE-269 (ACT-333679) has been investigated in liver microsomes and hepatocytes of rats, dogs, and monkeys. selexipag prostaglandin I2 receptor Rattus norvegicus