Protein Name prostaglandin I2 receptor
Organism Rattus norvegicus
Gene ID 292661
Gene Symbol

Ptgir

UniProt P43253 (PI2R_RAT)
Relationships Total Number of functionally related compound(s) : 28
Total Number of Articles : 35
Description

prostaglandin I2 receptor

Gene Summary

Predicted to enable prostacyclin receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Predicted to act upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • prostacyclin receptor
  • PGI receptor
  • PGI2 receptor
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Properties