Title : Differential Protein Dynamics of Regulators of G-Protein Signaling: Role in Specificity of Small-Molecule Inhibitors.

Pub. Date : 2018 Mar 7

PMID : 29460621






1 Functional Relationships(s)
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1 Hydrogen-deuterium exchange (HDX) studies and molecular dynamics (MD) simulations were used to probe the dynamics of RGS4, RGS8, and RGS19, three RGS proteins inhibited at a range of potencies by TDZDs. tdzds regulator of G protein signaling 4 Homo sapiens