Pub. Date : 2019
PMID : 29437011
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Oestradiol treatment reduced L-Arg concentration (p<0.01), iNOS mRNA (p<0.01) and protein (p<0.001) expression, level of RhoA (p<0.05) and AT1R (p<0.001) protein. | Estradiol | angiotensin II receptor, type 1a | Rattus norvegicus |
| 2 | CONCLUSION: Our results suggest that oestradiol in vivo regulates cardiac iNOS expression via the PI3K/Akt signaling pathway, through attenuation of RhoA and AT1R. | Estradiol | angiotensin II receptor, type 1a | Rattus norvegicus |