Pub. Date : 2018 Nov
PMID : 29427172
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Up-regulation of Ca2+/CaMKII/CREB signaling in salicylate-induced tinnitus in rats. | Salicylates | cAMP responsive element binding protein 1 | Rattus norvegicus |
| 2 | Compared with rats in NC and NS groups, salicylate administration significantly elevated CaM, NR2B, phospho-CaMKII and phospho-CREB expression in auditory cortex from tinnitus model group (p < 0.05), and the free intracellular Ca2+ concentrations (p < 0.05). | Salicylates | cAMP responsive element binding protein 1 | Rattus norvegicus |
| 3 | Our data reveal that salicylate administration causes tinnitus symptoms and elevates Ca2+/CaMKII/CREB signaling pathway in auditory cortex cells. | Salicylates | cAMP responsive element binding protein 1 | Rattus norvegicus |