Pub. Date : 2018 Apr
PMID : 29421708
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2. | Flavonoids | carboxylesterase 2 | Homo sapiens |
| 2 | In this study, more than fifty flavonoids were collected to assay their inhibitory effects against hCE2 using a fluorescence-based method. | Flavonoids | carboxylesterase 2 | Homo sapiens |
| 3 | Among all tested flavonoids, 5,6-dihydroxyflavone displayed the most potent inhibitory effect against hCE2 with the IC50 value of 3.50 muM. | Flavonoids | carboxylesterase 2 | Homo sapiens |
| 4 | All these findings are very helpful for the medicinal chemists to design and develop more potent and highly selective flavonoid-type hCE2 inhibitors. | Flavonoids | carboxylesterase 2 | Homo sapiens |