Title : Berberine inhibits the ischemia-reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3-kinase/RAC-α serine/threonine-protein kinase and nuclear factor-κB signaling pathways.

Pub. Date : 2018 Feb

PMID : 29403554






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1 In conclusion, the results of the present study indicate that berberine inhibits inflammatory responses through the NF-kappaB signaling pathway and suppresses the apoptosis of myocardial cells via the PI3K/AKT signaling pathway in a mouse model of ischemia-reperfusion injury. Berberine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus