Pub. Date : 2018
PMID : 29393133
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For many years, hyperuricemia was attributed to the effects of insulin resistance to reduce urinary excretion of uric acid, and it was believed that uric acid may not have any causal role in the metabolic syndrome. | Uric Acid | insulin | Homo sapiens |
| 2 | The mechanism for uric acid-induced insulin resistance appears to be mediated by the development of mitochondrial oxidative stress and impairment of insulin-dependent stimulation of nitric oxide in endothelial cells. | Uric Acid | insulin | Homo sapiens |
| 3 | Pilot studies in humans have reported a potential benefit of lowering serum uric acid on insulin resistance. | Uric Acid | insulin | Homo sapiens |