Title : The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice.

Pub. Date : 2018 May 1

PMID : 29390063






2 Functional Relationships(s)
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1 Pretreatment with pramipexole (PPX), a preferential D3R agonist, showed antidepressant effects on LPS-induced depression-like behavior through preventing changes in LPS-induced proinflammatory cytokines (tumour necrosis factor-alpha, interleukin-1beta, and interleukin-6), BDNF, and ERK1/2-CREB signaling pathway in the VTA and NAc. Pramipexole interleukin 6 Mus musculus
2 Pretreatment with pramipexole (PPX), a preferential D3R agonist, showed antidepressant effects on LPS-induced depression-like behavior through preventing changes in LPS-induced proinflammatory cytokines (tumour necrosis factor-alpha, interleukin-1beta, and interleukin-6), BDNF, and ERK1/2-CREB signaling pathway in the VTA and NAc. Pramipexole interleukin 6 Mus musculus