Pub. Date : 2018 Jul
PMID : 29388693
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of PPARdelta by GW501516, a specific PPARdelta agonist, inhibited glutamate release in BV-2 cells. | GW 501516 | peroxisome proliferator activator receptor delta | Mus musculus |
| 2 | Activation of PPARdelta by GW501516, a specific PPARdelta agonist, inhibited glutamate release in BV-2 cells. | GW 501516 | peroxisome proliferator activator receptor delta | Mus musculus |
| 3 | This effect of GW501516 was significantly blocked by shRNA-mediated knockdown of PPARdelta and by treatment with GSK0660, a specific PPARdelta antagonist, indicating that PPARdelta is associated with blockade of glutamate release. | GW 501516 | peroxisome proliferator activator receptor delta | Mus musculus |
| 4 | This effect of GW501516 was significantly blocked by shRNA-mediated knockdown of PPARdelta and by treatment with GSK0660, a specific PPARdelta antagonist, indicating that PPARdelta is associated with blockade of glutamate release. | GW 501516 | peroxisome proliferator activator receptor delta | Mus musculus |
| 5 | This effect of GW501516 was significantly blocked by shRNA-mediated knockdown of PPARdelta and by treatment with GSK0660, a specific PPARdelta antagonist, indicating that PPARdelta is associated with blockade of glutamate release. | GW 501516 | peroxisome proliferator activator receptor delta | Mus musculus |
| 6 | Additionally, GW501516-activated PPARdelta suppressed generation of reactive oxygen species and expression of gp91phox, a functional subunit of NADPH oxidase 2, in BV-2 cells stimulated with LPS. | GW 501516 | peroxisome proliferator activator receptor delta | Mus musculus |