Title : Anti-Interleukin-22-Neutralizing Antibody Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Mice.

Pub. Date : 2017

PMID : 29358851

1 Functional Relationships(s)
Compound Name
Protein Name
1 Anti-IL-22 nAb significantly alleviated the severity of hypertrophy, prevented systolic and diastolic abnormalities, reduced cardiac fibrosis, STAT3 and ERK phosphorylation, and downregulated the mRNA expression of IL-17, IL-6, IL-1beta, IFN-gamma, and TNF-alpha. nab tumor necrosis factor Mus musculus