Title : The nicotinic receptor drug sazetidine-A reduces alcohol consumption in mice without affecting concurrent nicotine consumption.

Pub. Date : 2018 May 1

PMID : 29355641






3 Functional Relationships(s)
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1 The nicotinic acetylcholine receptors (nAChRs) are critical for both alcohol and nicotine addiction mechanisms, since nAChR drugs that reduce nicotine consumption have been shown to also reduce alcohol consumption. Alcohols cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 The nicotinic acetylcholine receptors (nAChRs) are critical for both alcohol and nicotine addiction mechanisms, since nAChR drugs that reduce nicotine consumption have been shown to also reduce alcohol consumption. Alcohols cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 Collectively, these data suggest a novel role for the nAChR targets of sazetidine-A in specifically mediating alcohol consumption, separate from the involvement of nAChRs in mediating nicotine consumption. Alcohols cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus