Title : A Shared Pattern of β-Catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis.

Pub. Date : 2018 Apr

PMID : 29355514






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Using a library of human normal and diseased human lung samples, we identified a distinct signature of nuclear accumulation of beta-catenin phosphorylated at tyrosine 489 and epithelial cell cytosolic localization of beta-catenin phosphorylated at tyrosine 654 in early normal lung development and fibrotic lung diseases BPD and IPF. Tyrosine catenin beta 1 Homo sapiens
2 Using a library of human normal and diseased human lung samples, we identified a distinct signature of nuclear accumulation of beta-catenin phosphorylated at tyrosine 489 and epithelial cell cytosolic localization of beta-catenin phosphorylated at tyrosine 654 in early normal lung development and fibrotic lung diseases BPD and IPF. Tyrosine catenin beta 1 Homo sapiens
3 Nuclear beta-catenin phosphorylated at tyrosine 489 associated with an increased expression of Wnt target gene AXIN2, suggesting that the observed beta-catenin signature is of functional significance during normal development and injury repair. Tyrosine catenin beta 1 Homo sapiens
4 Nuclear beta-catenin phosphorylated at tyrosine 489 associated with an increased expression of Wnt target gene AXIN2, suggesting that the observed beta-catenin signature is of functional significance during normal development and injury repair. Tyrosine catenin beta 1 Homo sapiens