Pub. Date : 2018 Nov
PMID : 29355035
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simultaneous targeting therapy for lung metastasis and breast tumor by blocking the NF-kappaB signaling pathway using Celastrol-loaded micelles. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | To inhibit the metastasis and growth of breast tumor simultaneously, a Celastrol (Cela) loaded glucolipid-like conjugates (CSOSA/Cela) with alphavbeta3-ligand Tetraiodothyroacetic acid (TET) modification (TET-CSOSA/Cela) were established to block nuclear factor-kappa B (NF-kappaB) signaling pathway. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | To inhibit the metastasis and growth of breast tumor simultaneously, a Celastrol (Cela) loaded glucolipid-like conjugates (CSOSA/Cela) with alphavbeta3-ligand Tetraiodothyroacetic acid (TET) modification (TET-CSOSA/Cela) were established to block nuclear factor-kappa B (NF-kappaB) signaling pathway. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 4 | To inhibit the metastasis and growth of breast tumor simultaneously, a Celastrol (Cela) loaded glucolipid-like conjugates (CSOSA/Cela) with alphavbeta3-ligand Tetraiodothyroacetic acid (TET) modification (TET-CSOSA/Cela) were established to block nuclear factor-kappa B (NF-kappaB) signaling pathway. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 5 | To inhibit the metastasis and growth of breast tumor simultaneously, a Celastrol (Cela) loaded glucolipid-like conjugates (CSOSA/Cela) with alphavbeta3-ligand Tetraiodothyroacetic acid (TET) modification (TET-CSOSA/Cela) were established to block nuclear factor-kappa B (NF-kappaB) signaling pathway. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 6 | The results demonstrated that TET-CSOSA/Cela significantly suppressed Bcl-2 activation of lung metastatic cells and reduced MMP-9 expression of 4T1 breast tumor cells by blocking NF-kappaB. | celastrol | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |