Title : Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.

Pub. Date : 2018

PMID : 29344293






1 Functional Relationships(s)
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1 Additionally, HIF-1alpha inhibitor PX-478 repressed HSC pericyte functions, and ligustrazine inhibited the transcription of HIF-1alpha, which was diminished by GW9662. 2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide hypoxia inducible factor 1 subunit alpha Rattus norvegicus