Title : PCB118-Induced Cell Proliferation Mediated by Oxidative Stress and MAPK Signaling Pathway in HELF Cells.

Pub. Date : 2018 Jan-Mar

PMID : 29344011






4 Functional Relationships(s)
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1 PCB118-Induced Cell Proliferation Mediated by Oxidative Stress and MAPK Signaling Pathway in HELF Cells. 2,3',4,4',5-pentachlorobiphenyl mitogen-activated protein kinase 3 Homo sapiens
2 The present study used human lung fibroblast (HELF) cells as a test model to evaluate the role of oxidative stress (OS) and extracellular signal-regulated kinases 1/2 (ERK1/2) protein in HELF cell proliferation exposed to PCB118. 2,3',4,4',5-pentachlorobiphenyl mitogen-activated protein kinase 3 Homo sapiens
3 It was found that PCB118 showed expression of ERK1/2 protein after 4 hours, while after 48 hours, the protein expression was less, indicating PCB toxicity to MAPK protein of HELF cell. 2,3',4,4',5-pentachlorobiphenyl mitogen-activated protein kinase 3 Homo sapiens
4 It was found that PCB118 showed expression of ERK1/2 protein after 4 hours, while after 48 hours, the protein expression was less, indicating PCB toxicity to MAPK protein of HELF cell. 2,3',4,4',5-pentachlorobiphenyl mitogen-activated protein kinase 3 Homo sapiens