Title : Mobilization of a splicing factor through a nuclear kinase-kinase complex.

Pub. Date : 2018 Feb 14

PMID : 29335301






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Although CLK1 facilitates such trafficking through the phosphorylation of serine-proline dipeptides in the prototype SR protein SRSF1, an unrelated enzyme known as SR protein kinase 1 (SRPK1) performs the same function but does not efficiently modify these dipeptides in SRSF1. Dipeptides CDC like kinase 1 Homo sapiens
2 Diffusion from speckles is promoted by the formation of an SRPK1-CLK1 complex that facilitates dissociation of SRSF1 from CLK1 and enhances the phosphorylation of several serine-proline dipeptides in this SR protein. Dipeptides CDC like kinase 1 Homo sapiens