Protein Name CDC like kinase 1
Organism Homo sapiens
Gene ID 1195
Gene Symbol

CLK1

UniProt P49759 (CLK1_HUMAN)
Relationships Total Number of functionally related compound(s) : 89
Total Number of Articles : 72
Description

CDC like kinase 1

Gene Summary

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

synonyms
  • dual specificity protein kinase CLK1
  • CDC28/CDC2-like kinase
  • protein tyrosine kinase STY
Click to show/hide the synonyms
Properties