Pub. Date : 2017
PMID : 29332582
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Applying a ligand-based approach, the triazinone core emerged as a suitable scaffold to simultaneously bind the aspartic dyad of BACE-1 and the ATP site of GSK-3beta, leading to a series of small molecules endowed with a balanced micromolar affinity and a promising pharmacokinetic profile. | triazinone | beta-secretase 1 | Homo sapiens |