| Protein Name | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13162 |
| Gene Symbol | Slc6a3 |
| UniProt | Q61327 (SC6A3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
279
Total Number of Articles : 545 |
Description |
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 |
| Gene Summary |
Enables dopamine binding activity; dopamine:sodium symporter activity; and neurotransmitter transmembrane transporter activity. Involved in dopamine uptake; hyaloid vascular plexus regression; and neurotransmitter uptake. Acts upstream of or within several processes, including dopamine metabolic process; lactation; and prepulse inhibition. Located in axon terminus and cell surface. Is expressed in genitourinary system; nervous system; spleen; and submandibular gland. Used to study Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and schizophrenia. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; classic dopamine transporter deficiency syndrome; mild cognitive impairment; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |