Pub. Date : 2017
PMID : 29311817
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The presence of amyloid beta (Abeta) has been shown to disrupt gliotransmission, neurotransmitter uptake, and alter calcium signaling in astrocytes. | Calcium | amyloid beta precursor protein | Homo sapiens |
| 2 | Additionally, Abeta induces the appearance of oxidative stress (OS) and production of reactive oxygen species and reactive nitrogen species in astrocytes, affecting among others, intracellular calcium levels, NADPH oxidase (NOX), NF-kappaB signaling, glutamate uptake (increasing the risk of excitotoxicity) and mitochondrial function. | Calcium | amyloid beta precursor protein | Homo sapiens |