Title : Chaperone effect of sulfated disaccharide from heparin on mutant iduronate-2-sulfatase in mucopolysaccharidosis type II.

Pub. Date : 2018 Feb

PMID : 29289480






1 Functional Relationships(s)
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1 However, a chaperone compound for mucopolysaccharidosis type II (MPS II), which is an X-linked lysosomal storage disorder characterized by a deficiency of iduronate-2-sulfatase (IDS) and the accumulation of glycosaminoglycans (GAGs), has still not been developed. Glycosaminoglycans iduronate 2-sulfatase Homo sapiens