Title : Humanin decreases mitochondrial membrane permeability by inhibiting the membrane association and oligomerization of Bax and Bid proteins.

Pub. Date : 2018 Jun

PMID : 29265109






1 Functional Relationships(s)
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1 By using single-molecule fluorescence and Forster resonance energy transfer techniques, we showed that Bax was mainly present as monomers, dimers and tetramers in lipid bilayers, while truncated Bid (tBid) enhanced the membrane association and tetramerization of Bax. tBID BH3 interacting domain death agonist Homo sapiens