Title : Cardioprotective Mechanisms of Exenatide in Isoprenaline-induced Myocardial Infarction: Novel Effects on Myocardial α-Estrogen Receptor Expression and IGF-1/IGF-2 System.

Pub. Date : 2018 Mar

PMID : 29256971






4 Functional Relationships(s)
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1 Cardioprotective Mechanisms of Exenatide in Isoprenaline-induced Myocardial Infarction: Novel Effects on Myocardial alpha-Estrogen Receptor Expression and IGF-1/IGF-2 System. Exenatide insulin-like growth factor 1 Rattus norvegicus
2 Moreover, modulation of insulin-like growth factor-1/2 (IGF-1/IGF-2) system by exenatide, and the consequent effect on cardiomyocyte apoptosis, is yet to be established. Exenatide insulin-like growth factor 1 Rattus norvegicus
3 Moreover, modulation of insulin-like growth factor-1/2 (IGF-1/IGF-2) system by exenatide, and the consequent effect on cardiomyocyte apoptosis, is yet to be established. Exenatide insulin-like growth factor 1 Rattus norvegicus
4 Current study showed that the GLP-1R agonist exenatide exerted cardioprotection associated with upregulation of ERalpha and modulation of IGF-1/IGF-2 signaling in favor of antiapoptosis. Exenatide insulin-like growth factor 1 Rattus norvegicus