Title : Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities.

Pub. Date : 2018 Mar

PMID : 29254698






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2) catalyze the commitment step of the kynurenine (KYN) metabolic pathway. Kynurenine tryptophan 2,3-dioxygenase Homo sapiens
2 Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2) catalyze the commitment step of the kynurenine (KYN) metabolic pathway. Kynurenine tryptophan 2,3-dioxygenase Homo sapiens
3 Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2) catalyze the commitment step of the kynurenine (KYN) metabolic pathway. Kynurenine tryptophan 2,3-dioxygenase Homo sapiens
4 Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2) catalyze the commitment step of the kynurenine (KYN) metabolic pathway. Kynurenine tryptophan 2,3-dioxygenase Homo sapiens