Title : Phenformin has anti-tumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer.

Pub. Date : 2017 Nov 21

PMID : 29245964






1 Functional Relationships(s)
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1 Lastly, phenformin inhibited tumor growth in an orthotopic mouse model of serous OC, coincident with decreased Ki-67 staining and phosphorylated-S6 expression and increased expression of caspase 3 and phosphorylated-AMPK. Phenformin caspase 3 Mus musculus