Title : The role of sildenafil in the development of transplant arteriosclerosis in rat aortic grafts.

Pub. Date : 2017

PMID : 29218089






2 Functional Relationships(s)
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1 Moreover, sildenafil dramatically decreased the expression of transforming growth factor-beta1 (TGF-beta1), vascular endothelial growth factor (VEGF), and alpha-smooth muscle actin (alpha-SMA) in the grafted aortas and increased the concentrations of cyclic guanosine monophosphate (cGMP) and endothelial nitric oxide synthase (eNOS) in serum. Sildenafil Citrate vascular endothelial growth factor A Rattus norvegicus
2 Moreover, sildenafil dramatically decreased the expression of transforming growth factor-beta1 (TGF-beta1), vascular endothelial growth factor (VEGF), and alpha-smooth muscle actin (alpha-SMA) in the grafted aortas and increased the concentrations of cyclic guanosine monophosphate (cGMP) and endothelial nitric oxide synthase (eNOS) in serum. Sildenafil Citrate vascular endothelial growth factor A Rattus norvegicus