Pub. Date : 2017 Dec 1
PMID : 29199977
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | K-Ras, a molecular switch that regulates cell growth, apoptosis and metabolism, is activated when it undergoes a conformation change upon binding GTP and is deactivated following the hydrolysis of GTP to GDP. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |
| 2 | Here, crystal structures of G12A K-Ras in complex with GDP, GTP, GTPgammaS and GppNHp, and of Q61A K-Ras in complex with GDP, are reported. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |
| 3 | Here, crystal structures of G12A K-Ras in complex with GDP, GTP, GTPgammaS and GppNHp, and of Q61A K-Ras in complex with GDP, are reported. | Guanosine Diphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |