Title : The flavonoid quercetin inhibits titanium dioxide (TiO2)-induced chronic arthritis in mice.

Pub. Date : 2018 Mar

PMID : 29197723






1 Functional Relationships(s)
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1 The protective analgesic and anti-inflammatory mechanisms of quercetin included the inhibition of TiO2-induced neutrophil and macrophage recruitment, proteoglycan degradation, oxidative stress, cytokine production (TNF-alpha, IL-1beta, IL-6, and IL-10), COX-2 mRNA expression, and bone resorption as well as activation of Nrf2/HO-1 signaling pathway. Quercetin tumor necrosis factor Mus musculus