Pub. Date : 2017 Nov 3
PMID : 29190954
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclooxygenase-2 mediated synergistic effect of ursolic acid in combination with paclitaxel against human gastric carcinoma. | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 2 | Ursolic acid (UA) induces apoptosis in gastric cancer cells by inhibiting cyclooxygenase-2 (COX-2). | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 3 | Ursolic acid (UA) induces apoptosis in gastric cancer cells by inhibiting cyclooxygenase-2 (COX-2). | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 4 | Ursolic acid (UA) induces apoptosis in gastric cancer cells by inhibiting cyclooxygenase-2 (COX-2). | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 5 | Ursolic acid (UA) induces apoptosis in gastric cancer cells by inhibiting cyclooxygenase-2 (COX-2). | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 6 | Combined delivery of UA and PTX synergistically reduced cell proliferation and induced apoptosis in these cells by lowering COX-2, PCNA, and Bcl-2 expression and by increasing Bax expression. | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 7 | These results indicate that the synergistic inhibition of proliferation and induction of apoptosis by UA and PTX may be induced by reducing COX-2 expression in gastric cancer cells. | ursolic acid | prostaglandin-endoperoxide synthase 2 | Homo sapiens |